The largest employers in St. Louis include many companies of differing types of business. With a population of 2,812,571 people, St. Louis is a large enough city to guarantee many job opportunities in the area, including Downtown St. Louis. Even with all of the varied job opportunities, the health care field seems to dominate the list of jobs in St Louis.

BJC HealthCare is at the top of the list of largest employers in St Louis, with 26,531 employees. SSM Healthcare is near the top of the list, with 12,102 people employed there.

Boeing, the airplane manufacturer, has 16,000 employees. Nearby Scott Air Force Base, a United States Military Base, employs 14,150 people in St Louis.

Wal-Mart, the retail giant, is also a giant of employment in the St Louis area. Wal-Mart employs 13,400 people, making it one of the best places to work in St Louis. Schnuck Markets, Inc., another retailer, has 10,500 people working for its headquarters in St Louis.

The United States Postal Service has a large presence in Saint Louis, employing 12,700 people. This makes it the fifth largest employer in the city.

Washington University in Saint Louis is a very well known university, and employs 12,390. It is number six on the list of the largest employers in St Louis.

The Archdiocese of St. Louis is a large religious organization that provides jobs for 9,912 people living in St Louis.

AT&T, the telecommunications giant is headquartered in Dallas, Texas, yet employs 8,990 people in its offices in St. Louis, making it the tenth largest employer for that city. AT&T is known all over the world, but its presence in St Louis is a benefit for the city.

Some of the best places to work in St. Louis are very large businesses. These large companies are providing many people with jobs in St. Louis, the surrounding area and Downtown St. Louis.